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Article Dans Une Revue International Journal of Developmental Biology Année : 2020

Reciprocal interactions between mesenchymal stem cells and macrophages

Résumé

Mesenchymal stem cells (MSCs) are used as therapeutic agents for the treatment of a wide spectrum of diseases, as well as for the regeneration and healing of burns and wounds. MSCs have an immunomodulatory effect and influence the phenotype and functions of immune cells, including macrophages, which in turn prime and license the MSCs. We discuss the new findings on the feedback loop between MSCs and macrophages and its consequences on the outcome of MSC therapies. © 2020 UPV/EHU Press.

Dates et versions

hal-03102623 , version 1 (07-01-2021)

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M. Kloc, A. Uosef, M. Leśniak, J.Z. Kubiak, R.M. Ghobrial. Reciprocal interactions between mesenchymal stem cells and macrophages. International Journal of Developmental Biology, 2020, 64 (11-12), pp.465-469. ⟨10.1387/ijdb.200242jc⟩. ⟨hal-03102623⟩
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