%0 Journal Article %T Influence of severe knee pain, meniscus surgery and knee arthroplasty on physical ability an observational study of 114 949 adults in the CONSTANCES cohort %+ Cohortes épidémiologiques en population (CONSTANCES) %+ Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA) %+ Hôpital Avicenne [AP-HP] %+ Institut de recherche en santé, environnement et travail (Irset) %A Valter, Remi %A Godeau, Diane %A Leclerc, Annette %A Descatha, Alexis %A Fadel, Marc %Z ANR-11-INBS-0002, Ministry of Research %Z Constances, Caisse nationale d’assurance maladie %Z CapaciT project AAP2014, IReSP %< avec comité de lecture %@ 2044-6055 %J BMJ Open %I BMJ Publishing Group %V 9 %N 12 %P e031549 %8 2019-12 %D 2019 %R 10.1136/bmjopen-2019-031549 %M 31843828 %K surgery %K self-reported health %K knee %K occupational %K pain %Z Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system %Z Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO] %Z Life Sciences [q-bio]/Santé publique et épidémiologieJournal articles %X Background - The knee is one of the major sites of musculoskeletal pain, yet few large-scale studies have evaluated the impact of knee disorders on physical limitations. Our objective was to describe this impact in a large-scale population study. Methods - We included subjects of working age from the CONSTANCES cohort, from its inception. Four groups were distinguished according to their medical history: whether they had knee arthroplasty (KA), meniscus surgery, severe knee pain, or none of these. Outcomes assessed for physical limitations were self-reported limitations in the last 6 months due to health problems, limitation on carrying 5 kg on 10 m and a 3-metre length rapid gait speed test (for participants aged >45). Associations between knee groups and patients' characteristics and physical limitations were analysed using logistic regression. Robust associations were deemed relevant if their ORs were higher than 2 and their p value lower than 0.0001. Results - Of the 114 949 individuals, 99 052 (86.2%) were in the 'no pain and no surgery' group, 14 740 (12.8%) were in the severe knee pain group, 1019 (0.89%) had meniscus surgery and 138 (0.12%) had KA. Severe knee pain and KA groups showed a similar profile (they were less at work, reported more deterioration in their health and had more limitations).Conclusion - Almost 14% of the sample had knee disorders. Subjects reporting severe knee pain or who had KA reported more important physical limitations then subjects who reported neither severe knee pain nor knee surgery. %G English %2 https://univ-rennes.hal.science/hal-02441221/document %2 https://univ-rennes.hal.science/hal-02441221/file/Valter-2019-BMJOpen.pdf %L hal-02441221 %U https://univ-rennes.hal.science/hal-02441221 %~ UNIV-RENNES1 %~ UNIV-ANGERS %~ APHP %~ SANTE_PUB_INSERM %~ IFR140 %~ CONSTANCES %~ IRSET %~ UVSQ %~ STATS-UR1 %~ IRSET-TREC %~ IRSET-NEED %~ IRSET-TNGC %~ UR1-UFR-SVE %~ UR1-HAL %~ UR1-SDV %~ INSERM-SACLAY %~ UNIV-PARIS-SACLAY %~ UVSQ-SACLAY %~ IRSET-10 %~ TEST-UR-CSS %~ UNIV-RENNES %~ VIMA %~ UVSQ-UPSACLAY %~ ANR %~ UR1-BIO-SA %~ TEST3-HALCNRS