%0 Book Section %T RhoA pathway and actin regulation of the golgi/centriole complex %+ The University of Texas M.D. Anderson Cancer Center [Houston] %+ University of Houston %+ Institut de Génétique et Développement de Rennes (IGDR) %A Kloc, Malgorzata %A Uosef, Ahmed %A Wosik, Jarek %A Kubiak, Jacek, Z. %A Ghobrial, Rafik, Mark %Z University of Houston, UHMinistry of National Defense, MND 571/2016/DAWilliam and Ella Owens Medical Research FoundationNIH P30CA0166725508/2017/DA %@ 978-3-030-23173-6 %B The Golgi Apparatus and Centriole. Results and Problems in Cell Differentiation %I Springer Verlag %V 67 %P 81-93 %8 2019-08-22 %D 2019 %R 10.1007/978-3-030-23173-6_5 %M 31435793 %K actin %K RhoA guanine nucleotide binding protein %K actin filament %K centriole %K Golgi complex %K metabolism %K Actin Cytoskeleton %K Actins %K Centrioles %K Golgi Apparatus %K rhoA GTP-Binding Protein %Z Life Sciences [q-bio]Book sections %X In vertebrate cells, the Golgi apparatus is located in close proximity to the centriole. The architecture of the Golgi/centriole complex depends on a multitude of factors, including the actin filament cytoskeleton. In turn, both the Golgi and centriole act as the actin nucleation centers. Actin organization and polymerization also depend on the small GTPase RhoA pathway. In this chapter, we summarize the most current knowledge on how the genetic, magnetic, or pharmacologic interference with RhoA pathway and actin cytoskeleton directly or indirectly affects architecture, structure, and function of the Golgi/centriole complex. %G English %2 https://univ-rennes.hal.science/hal-02309655/document %2 https://univ-rennes.hal.science/hal-02309655/file/Kloc_et%20al_2019_RhoA%20Pathway%20and%20Actin%20Regulation%20of%20the%20Golgi%20Centriole%20Complex.pdf %L hal-02309655 %U https://univ-rennes.hal.science/hal-02309655 %~ UNIV-RENNES1 %~ CNRS %~ IFR140 %~ IGDR %~ STATS-UR1 %~ IGDR-CC %~ UR1-UFR-SVE %~ UR1-HAL %~ UR1-SDV %~ TEST-UR-CSS %~ UNIV-RENNES %~ TEST-HALCNRS %~ UR1-BIO-SA