This paper proposes a new scheme for the generation and transmission of a MIMO-OFDM signal over optical fiber using a single local oscillator (LO) at 15 GHz. This technique is based on subcarrier multiplexing and Optical Carrier Suppression (OCS) modulation using both Dual-Parallel Mach–Zehnder Modulator (DP-MZM) and Dual-Drive Mach–Zehnder Modulator (DD-MZM). DP-MZM is used to multiplex the MIMO-OFDM signals while DD-MZM is used to generate the 90 GHz signal by quadrupling. The realistic and global simulation of the complete system is performed to predict the behavior of a Radio over Fiber (RoF) system prior to its realization. The optical and wireless channels are based on Single Mode Fiber (SMF) and Triple-S-and-Valenzuela (TSV) models, respectively. We have exploited the allocated 7 GHz in the 60 GHz band for unlicensed use and we have successfully achieved 50km SMF followed by 3m wireless link at 70Gb/s. In comparison with traditional methods, the technique proposed combines better performance at relatively low-cost.