A Dienyl Boronate-Aryl Nitroso Ene Reaction Entry to C-Pyrrolyl Nitrones and Subsequent Conversion to Isoxazolidines - Université de Rennes Accéder directement au contenu
Article Dans Une Revue ChemistrySelect Année : 2018

A Dienyl Boronate-Aryl Nitroso Ene Reaction Entry to C-Pyrrolyl Nitrones and Subsequent Conversion to Isoxazolidines

Résumé

A new cascade reaction to access C-pyrrolyl nitrones en route to isoxazolidines is reported; a process that involves four successive steps, the first key step being an ene-reaction of a 3-methyl-1,3-dienylboronate ester with an aryl nitroso compounds to derive uncommon 1,3-dipoles which react with various alkenes to access isoxazolidines. The scope and mechanism of the cascade sequence is discussed.

Domaines

Chimie

Dates et versions

hal-01807080 , version 1 (04-06-2018)

Identifiants

Citer

Ludovic Eberlin, Aurélie Macé, Andrei S. Batsanov, Bertrand Carboni, Andrew Whiting. A Dienyl Boronate-Aryl Nitroso Ene Reaction Entry to C-Pyrrolyl Nitrones and Subsequent Conversion to Isoxazolidines. ChemistrySelect, 2018, 3 (16), pp.4557-4561. ⟨10.1002/slct.201800945⟩. ⟨hal-01807080⟩
26 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More