%0 Journal Article
%T A Meta-Analysis of Outcomes After In Situ Reconstructions for Aortic Graft Infection
%+ Université Nice Sophia Antipolis (1965 - 2019) (UNS)
%+ Aide à la Décision pour une Médecine Personnalisé - Laboratoire de Biostatistique, Epidémiologie et Recherche Clinique - EA 2415 (AIDMP)
%+ Unité de Chirurgie Vasculaire, CHU Lyon,
%+ Hôpital Saint-André
%+ Département des Maladies Infectieuses [CH Tourcoing] (Hôpital Gustave Dron)
%+ Service de bactériologie et hygiène hospitalière [Nantes]
%+ CH Béziers
%+ Pathogénie des Staphylocoques – Staphylococcal Pathogenesis (StaPath)
%A Batt, Michel
%A Feugier, Patrick
%A Camou, Fabrice
%A Coffy, Amandine
%A Senneville, Eric
%A Caillon, Jocelyne
%A Calvet, Brigitte
%A Chidiac, Christian
%A Laurent, Frédéric
%A Revest, Matthieu
%A Daures, Jean Pierre
%A For Vascular Graft Infection, Research Group
%< avec comité de lecture
%@ 0003-3197
%J Angiology
%I SAGE Publications
%V 69
%N 5
%P 370-379
%8 2018-05
%D 2018
%R 10.1177/0003319717710114
%M 28578619
%K reconstruction
%K aortic
%K graft
%K in situ
%K infection
%Z Life Sciences [q-bio]Journal articles
%X Objective - To confirm the advantage of in situ reconstruction (ISR) over extra-anatomic reconstruction (EAR) for aortic graft infection and determine the most appropriate conduit including autogenous veins, cryopreserved allografts, and synthetic prosthesis (standard, rifampicin of silver polyesters).
Methods - A meta-analysis was conducted with rate of mortality, graft occlusion, amputation, and reinfection. A meta-regression was performed with 4 factors: patients' age, presence of prosthetic-duodenal fistula (PDF), virulent organisms, or nonvirulent organisms.
Results - In situ reconstruction over EAR seems to favor all events. For the 5 conduits used for ISR, according to operative mortality, age of the patients looks to have a positive correlation only for silver polyester and no conduit present any advantage in the presence of PDF. Reinfection seems to be not significantly different for the 5 conduits, and only autogenous veins appear to have a positive correlation with infecting organisms.
Conclusion - In situ reconstruction may be considered as first-line treatment. Our results suggest that silver polyesters appear to be most appropriate for older patients, and in order to limit reinfection, autogenous veins are probably the most suitable conduit.
%G English
%L hal-01771414
%U https://univ-rennes.hal.science/hal-01771414
%~ UNIV-ST-ETIENNE
%~ ENS-LYON
%~ UNICE
%~ UNIV-NANTES
%~ CNRS
%~ UNIV-LYON1
%~ UNIV-MONTP1
%~ CIC
%~ STATS-UR1
%~ UR1-UFR-SVE
%~ UR1-SDV
%~ MIPS
%~ UNIV-MONTPELLIER
%~ UNIV-COTEDAZUR
%~ UNIV-RENNES
%~ CIRI
%~ UDL
%~ UNIV-LYON
%~ TEST-HALCNRS
%~ UR1-BIO-SA
%~ CIRI-F-VANDENESCH-STAPATH
%~ NANTES-UNIVERSITE
%~ UNIV-NANTES-AV2022
%~ UM-2015-2021