%0 Journal Article %T A Meta-Analysis of Outcomes After In Situ Reconstructions for Aortic Graft Infection %+ Université Nice Sophia Antipolis (1965 - 2019) (UNS) %+ Aide à la Décision pour une Médecine Personnalisé - Laboratoire de Biostatistique, Epidémiologie et Recherche Clinique - EA 2415 (AIDMP) %+ Unité de Chirurgie Vasculaire, CHU Lyon, %+ Hôpital Saint-André %+ Département des Maladies Infectieuses [CH Tourcoing] (Hôpital Gustave Dron) %+ Service de bactériologie et hygiène hospitalière [Nantes] %+ CH Béziers %+ Pathogénie des Staphylocoques – Staphylococcal Pathogenesis (StaPath) %A Batt, Michel %A Feugier, Patrick %A Camou, Fabrice %A Coffy, Amandine %A Senneville, Eric %A Caillon, Jocelyne %A Calvet, Brigitte %A Chidiac, Christian %A Laurent, Frédéric %A Revest, Matthieu %A Daures, Jean Pierre %A For Vascular Graft Infection, Research Group %< avec comité de lecture %@ 0003-3197 %J Angiology %I SAGE Publications %V 69 %N 5 %P 370-379 %8 2018-05 %D 2018 %R 10.1177/0003319717710114 %M 28578619 %K reconstruction %K aortic %K graft %K in situ %K infection %Z Life Sciences [q-bio]Journal articles %X Objective - To confirm the advantage of in situ reconstruction (ISR) over extra-anatomic reconstruction (EAR) for aortic graft infection and determine the most appropriate conduit including autogenous veins, cryopreserved allografts, and synthetic prosthesis (standard, rifampicin of silver polyesters).

Methods - A meta-analysis was conducted with rate of mortality, graft occlusion, amputation, and reinfection. A meta-regression was performed with 4 factors: patients' age, presence of prosthetic-duodenal fistula (PDF), virulent organisms, or nonvirulent organisms.

Results - In situ reconstruction over EAR seems to favor all events. For the 5 conduits used for ISR, according to operative mortality, age of the patients looks to have a positive correlation only for silver polyester and no conduit present any advantage in the presence of PDF. Reinfection seems to be not significantly different for the 5 conduits, and only autogenous veins appear to have a positive correlation with infecting organisms.

Conclusion - In situ reconstruction may be considered as first-line treatment. Our results suggest that silver polyesters appear to be most appropriate for older patients, and in order to limit reinfection, autogenous veins are probably the most suitable conduit. %G English %L hal-01771414 %U https://univ-rennes.hal.science/hal-01771414 %~ UNIV-ST-ETIENNE %~ ENS-LYON %~ UNICE %~ UNIV-NANTES %~ CNRS %~ UNIV-LYON1 %~ UNIV-MONTP1 %~ CIC %~ STATS-UR1 %~ UR1-UFR-SVE %~ UR1-SDV %~ MIPS %~ UNIV-MONTPELLIER %~ UNIV-COTEDAZUR %~ UNIV-RENNES %~ CIRI %~ UDL %~ UNIV-LYON %~ TEST-HALCNRS %~ UR1-BIO-SA %~ CIRI-F-VANDENESCH-STAPATH %~ NANTES-UNIVERSITE %~ UNIV-NANTES-AV2022 %~ UM-2015-2021