%0 Journal Article %T Microwave-assisted practical synthesis of 4-imino-3-phenyl-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thione derivatives and exploration of their biological activities %+ Institut des Sciences Chimiques de Rennes (ISCR) %+ Synthèse Caractérisation Analyse de la Matière (ScanMAT) %+ CHU Pontchaillou [Rennes] %+ Foie, métabolismes et cancer %+ Plate-forme ImPACcell (ImPACcell) %+ Station biologique de Roscoff [Roscoff] (SBR) %+ Laboratoire de Biologie Intégrative des Modèles Marins (LBI2M) %A Bouattour, A. %A Fakhfakh, M. %A Abid, S. %A Paquin, L. %A Corlu, A. %A Ruchaud, S. %A Bach, S. %A Ammar, H. %A Bazureau, J.-P. %A Le Guével, Rémy %< avec comité de lecture %@ 1551-7004 %J ARKIVOC - Online Journal of Organic Chemistry %I Arkat USA Inc %V 2017 %N 4 %P 291--302 %8 2017 %D 2017 %R 10.24820/ark.5550190.p010.040 %K Aminochromene %K Microwave %K Tumoral cell line %K Chromeno[2 %K 3-d]pyrimidine %K Kinase inhibition %K Iminocoumarin %Z Chemical SciencesJournal articles %X The synthesis of a series of new 4-imino-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thiones 6(a-f) without substituent in C-5 position using microwave dielectric heating is reported. These new compounds were obtained in three steps with good overall yields (21-50%). _figure presented_. %G English %L hal-01581215 %U https://univ-rennes.hal.science/hal-01581215 %~ UPMC %~ UNIV-RENNES1 %~ CNRS %~ INSA-RENNES %~ ENSC-RENNES %~ IFR140 %~ ISCR %~ SCR_ICMV %~ HL %~ U991 %~ U991-E2 %~ LBI2M %~ STATS-UR1 %~ BIOSIT %~ NUMECAN %~ UR1-SPM %~ INC-CNRS %~ NUMECAN-EXPRES %~ UR1-UFR-SVE %~ UR1-UFR-SPM %~ UR1-HAL %~ ISCR-CORINT %~ UR1-SDLM %~ UR1-SDV %~ SCANMAT %~ UPMC_POLE_3 %~ CMM %~ TEST-UNIV-RENNES %~ TEST-UR-CSS %~ UNIV-RENNES %~ INSA-GROUPE %~ SORBONNE-UNIVERSITE %~ SU-INF-2018 %~ SU-SCIENCES %~ SU-SCI %~ ISCR-CORINT2 %~ TEST-HALCNRS %~ SU-TI %~ UR1-MMS %~ UR1-BIO-SA %~ ALLIANCE-SU %~ TEST2-HALCNRS %~ TEST3-HALCNRS %~ SBR