%0 Journal Article %T Copper-Catalyzed Oxidative Dehydrogenative C(sp(3))-H Bond Amination of (Cyclo) Alkanes using NH-Heterocycles as Amine Sources %+ Institut des Sciences Chimiques de Rennes (ISCR) %+ Leibniz-Institut für Katalyse (LIKAT Rostock) %A Wang, Chang-Sheng %A Wu, Xiao-Feng %A Dixneuf, Pierre H. %A Soulé, Jean-François %Z China Scholarship Council (CSC) %Z Centre National de la Recherche Scientifique (CNRS) %Z Rennes Metropole %< avec comité de lecture %@ 1864-5631 %J ChemSusChem %I ChemPubSoc Europe/Wiley %V 10 %N 15 %P 3075-3082 %8 2017-08-10 %D 2017 %R 10.1002/cssc.201700783 %M 28612980 %K alkanes %K amination %K c-h activation %K copper %K heterocycles %Z Chemical Sciences/Organic chemistry %Z Chemical Sciences/CatalysisJournal articles %X A copper-catalyzed oxidative C(sp(3))-H/N-H coupling of NH-heterocycles with affordable (cyclo) alkanes has been developed. This procedure involves C(sp(3))-N bond formation through a radical pathway generated by homolytic cleavage of di-tert-butyl peroxide and trapping of the radical(s) by copper catalysts. The reaction tolerates a series of functional groups, such as bromo, fluoro, ester, ketone, nitrile, methyl, and methoxy. free-NH-containing indoles, pyrroles, pyrazoles, indazoles, and benzotriazoles are successfully N-alkylated. %G English %2 https://univ-rennes.hal.science/hal-01578538/document %2 https://univ-rennes.hal.science/hal-01578538/file/Wang%20et%20al.%20-%20Copper-Catalyzed%20Oxidative%20Dehydrogenative%20C%28sp3%29-.pdf %L hal-01578538 %U https://univ-rennes.hal.science/hal-01578538 %~ UNIV-RENNES1 %~ CNRS %~ INSA-RENNES %~ ENSC-RENNES %~ ISCR %~ SCR_OMC2012 %~ ISCR-OMC %~ STATS-UR1 %~ UR1-SPM %~ INC-CNRS %~ UR1-UFR-SPM %~ UR1-HAL %~ UR1-SDLM %~ TEST-UNIV-RENNES %~ TEST-UR-CSS %~ UNIV-RENNES %~ INSA-GROUPE %~ TEST-HALCNRS %~ UR1-MMS %~ TEST2-HALCNRS