@article{ursino:hal-01560222, TITLE = {{Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations}}, AUTHOR = {Ursino, Moreno and Zohar, Sarah and Lentz, Frederike and Alberti, Corinne and Friede, Tim and Stallard, Nigel and Comets, Emmanuelle}, URL = {https://univ-rennes.hal.science/hal-01560222}, JOURNAL = {{Biometrical Journal}}, PUBLISHER = {{Wiley-VCH Verlag}}, VOLUME = {59}, NUMBER = {4}, PAGES = {804-825}, YEAR = {2017}, MONTH = Jul, DOI = {10.1002/bimj.201600084}, KEYWORDS = {Dose-finding ; Dose-toxicity relationship ; Maximum Tolerated Dose ; pharmacokinetics ; Phase I clinical trials ; Dose-toxicity relationship ; Maximum tolerated dose ; Pharmacokinetics ; Phase I clinical trials}, PDF = {https://univ-rennes.hal.science/hal-01560222/file/Dose-finding%20methods%20for%20Phase.pdf}, HAL_ID = {hal-01560222}, HAL_VERSION = {v1}, }