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, CORC:FJA/NP-2015-109 and CORC:FJA/NP-2014-126) Association pour la Recherche sur le Cancer Epigenetic experiments were supported by a specific grant from, Ligue Contre le Cancer (Comité de la Corrèze et Haute Vienne), Agence Nationale de la Recherche (ANR: projet EpiSwitch-3?RR 2016)

G. Cancéropôle, A. Saintamand was supported by a grant from fondation ARC (DOC20150602943) N, 2014.

, Orientation Scientifique (Lebanon) and the municipality of Khiam (Lebanon). M. Cogné is supported by Institut Universitaire de France and Fondation pour la Recherche Médicale. We acknowledge the technological expertise of the Nice Sophia-Antipolis Functional Genomics Platform, supported by MICROENVIMET, FP7-HEALTHF2, the ARC, and the INCa. We thank Dr. P. Barbry for helpful discussions and support during this work. We thank S. Desforges and B. Remerand for help with animal care, 2008.