%0 Journal Article %T Prognostic value of pulmonary congestion assessed by lung ultrasound imaging during heart failure hospitalisation: A two-centre cohort study %+ Università degli Studi di Perugia = University of Perugia (UNIPG) %+ Centre d'investigation clinique plurithématique Pierre Drouin [Nancy] (CIC-P) %+ Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy] %+ Cardiovascular and Renal Clinical Trialists [Vandoeuvre-les-Nancy] (INI-CRCT) %+ French-Clinical Research Infrastructure Network - F-CRIN [Paris] (Cardiovascular & Renal Clinical Trialists - CRCT ) %+ Service de Cardiologie [CHRU Nancy] %+ Défaillance Cardiovasculaire Aiguë et Chronique (DCAC) %+ CIC-IT Rennes %+ Laboratoire Traitement du Signal et de l'Image (LTSI) %A Coiro, Stefano %A Porot, Guillaume %A Rossignol, Patrick %A Ambrosio, Giuseppe %A Carluccio, Erberto %A Tritto, Isabella %A Huttin, Olivier %A Lemoine, Simon %A Sadoul, Nicolas %A Donal, Erwan %A Zannad, Faiez %A Girerd, Nicolas %Z Boston Scientific %Z Novartis %Z Bayer %Z Johnson Johnson %Z Resmed %Z Pfizer %Z Angelini %Z Behring %Z Menarini %Z Merck %Z Takeda %Z AstraZeneca %Z Boehringer Ingelheim %Z GE Healthcare %Z Relypsa %Z Servier %< avec comité de lecture %@ 2045-2322 %J Scientific Reports %I Nature Publishing Group %V 6 %N 1 %P 39426 %8 2016-12-23 %D 2016 %R 10.1038/srep39426 %M 27995971 %K prediction %K recommendations %K natriuretic peptide %K echocardiography %K risk %K association %K task-force %K diastolic function %K clinical-assessment %K guidelines %Z Life Sciences [q-bio]Journal articles %X Pulmonary congestion assessed at discharge by lung ultrasonography predicts poor prognosis in heart failure (HF) patients. We investigated the association of B-lines with indices of hemodynamic congestion [BNP, E/e', pulmonary systolic arterial pressure (PAPs)] in HF patients, and their prognostic value overall and according to concomitant atrial fibrillation (AF), reduced (≤40%) ejection fraction (EF), and timing of quantification during hospitalisation for heart failure (HHF). In 110 HHF patients, B-lines were highly discriminative of BNP >400 pg/ml (AUC ≥ 0.80 for all), and moderately discriminative of PAPs >50 mmHg (AUC = 0.68, 0.56 to 0.80); conversely, B-lines poorly discriminated average E/e' ≥ 15, except at discharge. B-line count significantly predicted mid-term recurrent HHF or death (overall and in subgroups), regardless of AF status, EF, and timing of quantification during HHF (all p for interaction >0.10). regardless, B-lines ≥30 at discharge were most predictive of outcome (HR = 7.11, 2.06-24.48; p = 0.002) while B-lines ≥45 early during HHF were most predictive of outcome (HR = 9.20, 1.82-46.61; p = 0.007). Lung ultrasound was able to identify patients with high BNP levels, but not with increased E/e', also showing a prognostic role regardless of AF status, EF or timing of quantification; best B-line cut-off appears to vary according to the timing of quantification during hospitalization. %G English %L hal-01436294 %U https://univ-rennes.hal.science/hal-01436294 %~ UNIV-RENNES1 %~ LTSI %~ HL %~ CIC %~ STATS-UR1 %~ UNIV-LORRAINE %~ UR1-UFR-SVE %~ UR1-HAL %~ UR1-MATH-STIC %~ UR1-SDV %~ TEST-UNIV-RENNES %~ TEST-UR-CSS %~ DCAC-UL %~ UNIV-RENNES %~ BMS-UL %~ UR1-MATH-NUM %~ UR1-BIO-SA %~ TEST3-HALCNRS