Origine développementale de la santé et des maladies (DOHaD), environnement et épigénétique [DOHaD: epidemiological researches] - Université de Rennes Access content directly
Journal Articles Médecine/Sciences Year : 2016

Origine développementale de la santé et des maladies (DOHaD), environnement et épigénétique [DOHaD: epidemiological researches]

Abstract

Epidemiological researches in the field of DOHaD are in favor of a role of early environment, including chemical (pesticides), physical (air pollution), nutritional or psychosocial environment, on child and adult health. Disentangling the different factors of environment that may affect health, especially over time, and identifying critical periods of exposure remains a major challenge. The biological mechanisms involved remain elusive in human beings. Nevertheless, it seems that whatever the nature of the exposure, epigenetic mechanisms are currently discussed to explain how the environment may alter biological systems over time.

Dates and versions

hal-01274219 , version 1 (15-02-2016)

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Cyrille Delpierre, Johanna Lepeule, Sylvaine Cordier, Rémy Slama, Barbara Heude, et al.. Origine développementale de la santé et des maladies (DOHaD), environnement et épigénétique [DOHaD: epidemiological researches]. Médecine/Sciences, 2016, 32 (1), pp.21--26. ⟨10.1051/medsci/20163201005⟩. ⟨hal-01274219⟩
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