%0 Journal Article %T Aerobic Training Suppresses Exercise-induced Lipid Peroxidation and Inflammation in Overweight/Obese Adolescent Girls %+ Laboratoire Mouvement Sport Santé (M2S) %A Groussard, C %A Youssef, H %A Sophie, V %A Pincemail, J %A Jacob, C %A Moussa, E %A Fazah, A %A Cillard, Josiane %A Pineau, Jc %A Gratas-Delamarche, Arlette %< avec comité de lecture %J Pediatr Exerc Sci. %V 27 %N 1 %P 67-76 %8 2015-02 %D 2015 %R 10.1123/pes.2014-0008 %M 25387489 %Z Life Sciences [q-bio]Journal articles %X This study aimed to determine whether aerobic training could reduce lipid peroxidation and inflammation at rest and after maximal exhaustive exercise in overweight/obese adolescent girls. Thirty-nine adolescent girls (14-19 years old) were classified as non-obese or overweight/obese and then randomly assigned to either the non-trained or trained group (12-week multivariate aerobic training program). Measurements at the beginning of the experiment and at 3 months consisted of body composition, aerobic fitness (VO2peak) and the following blood assays: pre- and post-exercise lipid peroxidation (15F2?-isoprostanes [F2-Isop], lipid hydroperoxide [ROOH], oxidized LDL [ox-LDL]) and inflammation (myeloperoxidase [MPO]) markers. In the overweight/obese group, the training program significantly increased their fat-free mass (FFM) and decreased their percentage of fat mass (%FM) and hip circumference but did not modify their VO2peak. Conversely, in the non-trained overweight/obese group, weight and %FM increasedand VO2peak decreased, during the same period. Training also prevented exercise-induced lipid peroxidation and/or inflammation in overweight/obese girls (F2-Isop, ROOH, ox-LDL, MPO). In addition, in the trained overweight/obese group, exercise-induced changes in ROOH, ox-LDL and F2-Isop were correlated with improvements in anthropometric parameters (waist-to-hip ratio, %FM and FFM). In conclusion aerobic training increased tolerance to exercise-induced oxidative stress in overweight/obese adolescent girls partly as a result of improved body composition. %G English %L hal-01159358 %U https://univ-rennes.hal.science/hal-01159358 %~ UNIV-BREST %~ UNIV-RENNES1 %~ UR2-HB %~ ENS-CACHAN %~ IFR140 %~ STATS-UR1 %~ M2S %~ UR1-HAL %~ UR1-SHS %~ UNIV-PARIS-SACLAY %~ ENS-CACHAN-SACLAY %~ UNIV-RENNES2 %~ TEST-UNIV-RENNES %~ TEST-UR-CSS %~ UNIV-RENNES %~ UR1-BIO-SA %~ ENS-PARIS-SACLAY