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Brevet Année : 2012

Biomarkers for the prognosis and high-grade glioma clinical outcome

Résumé

The present invention relates to the identification and use of biomarkers with clinical relevance to high grade gliomas (HGGs). In particular, the invention provides the identity of four genes, CHAF1B, PDLIM4, EDNRB and HJURP, whose expression, at the transcriptome and proteome levels, is correlated with HGG grading and clinical survival outcome. Methods and kits are provided for using these biomarkers in the prognostication of HGGs, and in the selection and/or monitoring of treatment regimens.
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Dates et versions

hal-01117079 , version 1 (16-02-2015)

Identifiants

  • HAL Id : hal-01117079 , version 1

Citer

Jean Mosser, Marie De Tayrac, Marc Aubry. Biomarkers for the prognosis and high-grade glioma clinical outcome. United States, Patent n° : 20120129711. 2012. ⟨hal-01117079⟩
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