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Article Dans Une Revue Electronic Journal of Biotechnology Année : 2010

Improved growth model for two-stage continuous cultures of Lactobacillus helveticus

Résumé

An unstructured model for growth and lactic acid production during two-stage continuous cultures of Lactobacillus helveticus was previously developed. The Verlhust model was considered to describe growth kinetics. Production models was based on modified Luedeking-Piret expressions involving an inhibitory effect for the first stage (seed culture) and a nutritional limitation effect for the second stage (culture). To account for the decrease of the biomass concentration observed in the second stage, the dilution rate Dc was replaced by an exponential term of the dilution rate in the growth and product relations. Contrarily to the previous model, the important decrease of the biomass concentration observed at steady state in the second stage at high dilution rates, namely close to wash out, was correctly described by the new model. It also proved to satisfactory describes production data and volumetric productivity.
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Dates et versions

hal-00920292 , version 1 (18-12-2013)

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Citer

Abdallah Bouguettoucha, Béatrice Balannec, Saci Nacef, Abdeltif Amrane. Improved growth model for two-stage continuous cultures of Lactobacillus helveticus. Electronic Journal of Biotechnology, 2010, 13 (5), pp.1-13. ⟨10.2225/vol13-issue5-fulltext-16⟩. ⟨hal-00920292⟩
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