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Communication Dans Un Congrès Année : 2010

A trioventricular delay optimization in cardiac resynchronization therapy assessed by a computer model.

Résumé

A lumped-parameter model of the cardiovascular system is applied in this work to the analysis of the characteristics of mitral flow profiles, for different atrio-ventricular pacing configurations, in the context of cardiac resynchronization therapy (CRT). Primarily, a sensitivity analysis is performed on the main model parameters, so as to discern their influence on mitral flow. Parameter identification is then applied to reproduce pulsed-wave Doppler profiles of the mitral inflow acquired from three patients during post-operative CRT optimization sessions. The model is able to reproduce patient-specific morphological variations on mitral inflow profiles for different AVD values, providing relative mean squared errors reading 0.031, 0.068 and 0.076 for the three patients.
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Dates et versions

hal-00910933 , version 1 (28-11-2013)

Identifiants

  • HAL Id : hal-00910933 , version 1

Citer

Kevin Tse Ve Koon, Christophe Thebault, Virginie Le Rolle, Erwan Donal, Alfredo I. Hernández. A trioventricular delay optimization in cardiac resynchronization therapy assessed by a computer model.. IEEE Computing in Cardiology, Sep 2010, Belfast, Ireland. pp.333 - 336. ⟨hal-00910933⟩
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