%0 Conference Proceedings %T Oc031--Generic Substitution Of Antiepileptic Drug (Aed) And Loss Of Seizure Control: A Population-Based Case-Crossover Study %+ Centre d'Investigation Clinique [Rennes] (CIC) %+ Service de Neurologie [Rennes] = Neurology [Rennes] %A Polard, Elisabeth %A Happe, André %A Nowak, Emmanuel %A Biraben, Arnaud %A Oger, Emmanuel %Z Open access CC-BY %< avec comité de lecture %@ 0149-2918 %J Clinical Therapeutics %( The Proceedings of the 11th Conference of the European Association for Clinical Pharmacology and Therapeutics %B 11th Conference of the European Association for Clinical Pharmacology and Therapeutics %C Genève, Switzerland %I Elsevier %V 35 %N 8 %P e13 %8 2013-08-28 %D 2013 %R 10.1016/j.clinthera.2013.07.030 %Z Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyConference papers %X There are still controversies over pill substitution among AEDs: some studies claimed that switching between brand and generic AED (generic substitution) can lead to breakthrough seizures; other studies have refuted these concerns. France and some US states recommend limiting substitution of generic AED. We aimed at further estimating the association between generic substitution and loss of seizure control. %G English %2 https://univ-rennes.hal.science/hal-00874515/document %2 https://univ-rennes.hal.science/hal-00874515/file/Oc031-Generic-OpenAccess-licenceCC-BY.pdf %L hal-00874515 %U https://univ-rennes.hal.science/hal-00874515 %~ UNIV-RENNES1 %~ HL %~ CIC %~ CIC203 %~ STATS-UR1 %~ UR1-UFR-SVE %~ UR1-HAL %~ UR1-SDV %~ TEST-UNIV-RENNES %~ TEST-UR-CSS %~ UNIV-RENNES %~ UR1-BIO-SA