Studies of a furanoside as antimycobacterial agent loaded into a biodegradable PBAT/sodium caseinate support. - Université de Rennes Accéder directement au contenu
Article Dans Une Revue Carbohydrate Research Année : 2011

Studies of a furanoside as antimycobacterial agent loaded into a biodegradable PBAT/sodium caseinate support.

Résumé

An improved synthesis of n-octyl β-D-galactofuranoside was described using micro-wave activation. The resulting alkyl furanoside showed antibacterial activity against Mycobacterium smegmatis, a non-pathogenic model of Mycobacterium tuberculosis. It was further incorporated into a biodegradable PBAT/sodium caseinate polymer. The resulting biomaterial loaded with 5% of the pharmacophore retained the mycobacteriostatic properties and developed a mycobactericidal activity on contact and at the periphery of the film.

Dates et versions

hal-00752722 , version 1 (16-11-2012)

Identifiants

Citer

Laurent Legentil, Jean-Luc Audic, Richard Daniellou, Caroline Nugier-Chauvin, Vincent Ferrières. Studies of a furanoside as antimycobacterial agent loaded into a biodegradable PBAT/sodium caseinate support.. Carbohydrate Research, 2011, 346 (12), pp.1541-5. ⟨10.1016/j.carres.2011.04.025⟩. ⟨hal-00752722⟩
117 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More