Asymmetric Induction by Chiral Borate Anions in Enantioselective Hydrogenation using a Racemic Rh Binap Catalyst
Résumé
With a little help from my friend: Combination of the racemic binap ligand with enantiopure bis-(S)-binol-borate anion results in enantioselectivities up to 57 % ee in the rhodium-catalyzed asymmetric hydrogenation of dimethyl itaconate, which corresponds to 85 % of the asymmetric induction caused by the enantiopure binap ligand.