On the transition from the meiotic to mitotic cell cycle during early mouse development. - Université de Rennes Accéder directement au contenu
Article Dans Une Revue International Journal of Developmental Biology Année : 2008

On the transition from the meiotic to mitotic cell cycle during early mouse development.

Maria A Ciemerych
  • Fonction : Auteur
Anna Hupalowska
  • Fonction : Auteur
Marta Sikora-Polaczek
  • Fonction : Auteur
Zbigniew Polanski
  • Fonction : Auteur

Résumé

Here, we outline the mechanisms involved in the regulation of cell divisions during oocyte maturation and early cleavages of the mouse embryo. Our interest is focused on the regulation of meiotic M-phases and the first embryonic mitoses that are differently tuned and are characterized by specifically modified mechanisms, some of which have been recently identified. The transitions between the M-phases during this period of development, as well as associated changes in their regulation, are of key importance for both the meiotic maturation of oocytes and the further development of the mammalian embryo. The mouse is an excellent model for studies of the cell cycle during oogenesis and early development. Nevertheless, a number of molecular mechanisms described here were discovered or confirmed during the study of other species and apply also to other mammals including humans.

Dates et versions

hal-00277545 , version 1 (06-05-2008)

Identifiants

Citer

Jacek Kubiak, Maria A Ciemerych, Anna Hupalowska, Marta Sikora-Polaczek, Zbigniew Polanski. On the transition from the meiotic to mitotic cell cycle during early mouse development.. International Journal of Developmental Biology, 2008, 52 (2-3), pp.201-17. ⟨10.1387/ijdb.072337jk⟩. ⟨hal-00277545⟩
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