Controlled Ru (II) andamp- Rh (III) catalyzed [4+2] andamp- [4+1] carbo‐annulation via C–H Activation using Sulfoxonium ylide andamp- Maleimide: Facile access to Fused Benzoisoindole andamp- Spiroindanone
Résumé
A well‐ordered strategy of sulfoxonium ylides as a directing group as well as carbene source for the Ru‐catalysed [4+2] and Rh‐catalysed [4+1] carbo‐annulations with maleimides has been described. These novel methodologies have been successfully established for the synthesis of complex spiroindanones and benzoisoindoles containing compounds by the transition metal‐mediated C−H activation/functionalization reactions. Further, Rh‐catalysed [4+1] annulated compounds were obtained in the absence of any oxidant. A possible rationale for the remarkable divergent selectivity between the two catalysts has been proposed.
Origine | Fichiers produits par l'(les) auteur(s) |
---|